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KMID : 0359920110300060671
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Korean Journal of Nephrology
2011 Volume.30 No. 6 p.671 ~ p.675
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Maxillofacial Enlargement in Secondary Hyperparathyroidism Successfully Treated by Limited Parathyroidectomy and Paricalcitol
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Oh Se-Won
Lee Young-Mo
Kim Jeong-Yup
Wang Joon-Kwang
Jee Ko-Gang
Pyo Heui-Jung
Kwon Young-Joo
Suh Sang-Il
Kim Seong-Eun
Lee Jae-Bok
Lee Ji-Eun
Lee Seung-Won
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Abstract
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Maxillary enlargement is a rare complication of secondary hyperparathyroidism (SHPT). A 35-year-old Korean man undergoing chronic hemodialysis presented with a painless enlargement involving the maxilla and mandible. Plain radiography and CT scan showed bony expansion at the maxilla and mandible with multiple radiolucency. Serum intact parathyroid hormone (iPTH) was >1,600 pg/mL. Tc- 99m sestamibi (MIBI) parathyroid scan and neck sonogram were compatible with SHPT. He underwent limited parathyroidectomy and commenced a course of paricalcitol. Fifteen months after surgery, maxillary enlargement and bony resorptions involving both hands markedly improved. Thirty-six months after the surgery, the serum iPTH level was 109.3 pg/mL. This is the first report in Korea documenting a patient with maxillary enlargement in SHPT who was successfully treated with limited parathyroidectomy and paricalcitol.
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KEYWORD
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Renal osteodystrophy, Hyperparathyroidism, secondary, Maxillas
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